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API Intermediate
Key Products
No. Product Name CAS No. Application
1Rebaudioside M1220616-44-3Food Additive, Main Function: Used as a natural high-potency sweetener in food and beverage industry to substitute sucrose and partial artificial synthetic sweeteners.
2Rebaudioside A58543-16-1Food Additive, Main Function: Used as a natural high-potency sweetener in food and beverage industry to substitute sucrose and partial artificial synthetic sweeteners.
3Rebaudioside B58543-17-2Food Additive, Main Function: Used as a natural high-potency sweetener in food and beverage industry to substitute sucrose and partial artificial synthetic sweeteners.
4Rebaudioside D63279-13-0Food Additive, Main Function: Used as a natural high-potency sweetener in food and beverage industry to substitute sucrose and partial artificial synthetic sweeteners.
5Stevioside/Food Additive, Main Function: Used as a natural high-potency sweetener in food and beverage industry to substitute sucrose and partial artificial synthetic sweeteners.
6Glucosyl Stevioside GSG/Food Additive, Main Function: Used as a natural high-potency sweetener in food and beverage industry to substitute sucrose and partial artificial synthetic sweeteners.
7Salidroside10338-51-9API, Main Function: Applied to relieve altitude sickness, improve exercise endurance and protect cardiovascular and nervous systems.
8Fusidic Acid6990-06-3API, Main Function: For the treatment of infections caused by Gram-positive bacteria.
9Sodium Fusidate751-94-0API, Main Function: For the treatment of skin infections, eye infections and other related ailments.
10Riociguat625115-55-1API, Main Function: For the treatment of chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH).
11Vericiguat1350653-20-1API, Main Function: For the treatment of chronic heart failure.
12Teicoplanin61036-62-2API, Main Function: For the treatment of severe infections caused by Gram-positive bacteria.
13Orforglipron Hemicalciumhydrate3008544-96-2API, Main Function: For the treatment of type 2 diabetes mellitus and obesity.
14Resmetirom920509-32-6API, Main Function: For the treatment of non-alcoholic steatohepatitis (NASH).
Oncology
No. Product Name CAS No. Application
15Baricitinib1187594-09-7API, Main Function: Indicated for the treatment of moderate to severe rheumatoid arthritis (RA); it is also approved for immune-related disorders including atopic dermatitis, hospitalized COVID-19 patients and systemic lupus erythematosus (SLE).
16Ibrutinib936563-96-1API, Main Function: For the treatment of various B-cell malignancies.
17Tofacitinib citrate540737-29-9API, Main Function: For the treatment of moderate to severe rheumatoid arthritis (RA), active psoriatic arthritis (PsA) and ulcerative colitis (UC).
18Crizotinib877399-52-5API, Main Function: For the treatment of non-small cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK), ROS1 or MET genetic abnormalities.
19Cabozantinib Malate1140909-48-3API, Main Function: For the treatment of advanced renal cell carcinoma (RCC), hepatocellular carcinoma (HCC) and RET fusion-positive non-small cell lung cancer (NSCLC).
20Enzalutamide915087-33-1API, Main Function: For the treatment of castration-resistant prostate cancer (CRPC) and metastatic castration-sensitive prostate cancer (mCSPC).
21Lenvatinib Mesylate857890-39-2API, Main Function: For the treatment of differentiated thyroid carcinoma (DTC), unresectable hepatocellular carcinoma (HCC) and advanced renal cell carcinoma (RCC).
22Palbociclib571190-30-2API, Main Function: For the treatment of advanced or metastatic hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer.
23Regorafenib755037-03-7API, Main Function: For the treatment of metastatic colorectal cancer (mCRC), advanced gastrointestinal stromal tumor (GIST) and hepatocellular carcinoma (HCC).
24Ceritinib (LDK378)1032900-25-6API, Main Function: For the treatment of ALK-positive non-small cell lung cancer (NSCLC), especially for patients with drug resistance or intolerance to crizotinib, a first-generation ALK inhibitor.
25Afatinib Maleate850140-73-7API, Main Function: For the treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC).
26Gefitinib184475-35-2API, Main Function: For the treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC).
27Venetoclax (ABT-199)1257044-40-8API, Main Function: For the treatment of chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML).
28Apalutamide956104-40-8API, Main Function: For the treatment of non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic castration-sensitive prostate cancer (mCSPC).
Anti-infective
No. Product Name CAS No. Application
29Baloxavir Marboxil1985606-14-1API, Main Function: A novel anti-influenza agent classified as a cap-dependent endonuclease inhibitor, indicated for single-dose treatment of influenza A and B in patients aged 12 years and older.
30Tenofovir Alafenamide Fumarate1392275-56-7API, Main Function: For the treatment of chronic hepatitis B (CHB) and used as a key component in pre-exposure prophylaxis (PrEP) regimens against HIV.
31Mezlocillin51481-65-3API, Main Function: For the treatment of moderate to severe infections caused by susceptible bacteria, particularly systemic infections caused by Gram-negative bacteria (such as Pseudomonas aeruginosa, Enterobacteriaceae) and some Gram-positive bacteria.
Cardiova-scular
No. Product Name CAS No. Application
32Canagliflozin842133-18-0API, Main Function: For the treatment of type 2 diabetes mellitus and chronic heart failure with reduced ejection fraction (HFrEF).
33Empagliflozin864070-44-0API, Main Function: For the treatment of type 2 diabetes mellitus and chronic heart failure with reduced ejection fraction (HFrEF).
34Rivaroxaban366789-02-8API, Main Function: For the prevention and treatment of venous thromboembolism (VTE) and reduction of the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
35Sacubitril Valsartan Sodium936623-90-4API, Main Function: For the treatment of chronic heart failure with reduced ejection fraction (HFrEF).
36Edoxaban Tosylate Monohydrate1229194-11-9API, Main Function: For the prevention and treatment of stroke and systemic embolism in patients with non-valvular atrial fibrillation, and for the treatment and prevention of recurrence of deep vein thrombosis (DVT) and pulmonary embolism (PE).
Peptide
No. Product Name CAS No. Application
37Etelcalcetide1262780-97-1API, Main Function: For the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) undergoing hemodialysis.
38Tirzepatide2023788-19-2API, Main Function: For the treatment of type 2 diabetes mellitus and chronic weight management.
39Teriparatide99294-94-7API, Main Function: For the treatment of severe osteoporosis.
40Retatrutide2381089-83-2API, Main Function: For the treatment of type 2 diabetes mellitus and obesity.
41Liraglutide204656-20-2API, Main Function: For the treatment of type 2 diabetes mellitus and chronic weight management.
Other
No. Product Name CAS No. Application
42Parecoxib sodium198470-85-8API, Main Function: For the treatment of post-surgical pain.
43Apremilast608141-41-9API, Main Function: For the treatment of psoriatic arthritis (PsA), ankylosing spondylitis (AS), and moderate to severe plaque psoriasis.
44Aprepitant170729-80-3API, Main Function: For the prevention of chemotherapy-induced nausea and vomiting (CINV), particularly acute and delayed nausea and vomiting caused by highly emetogenic chemotherapy regimens such as cisplatin-containing protocols.
Riociguat intermediate
No. Product Name CAS No. Application
12-[1-[(2-fluorophenyl)Methyl]1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(phenylazo)-4,6-PyriMidinediaMine428854-23-3Pharmaceutical Intermediate, Main Function: For the synthesis of innovative drugs targeting hematological malignancies such as B-cell lymphoma and chronic lymphocytic leukemia.
2Methyl[4,6-diaMino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyriMidin-5-yl]carbaMate625115-52-8Pharmaceutical Intermediate, Main Function: For the synthesis of riociguat, a drug for the treatment of pulmonary arterial hypertension.
32-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyriMidine-4,5,6-triaMine428854-24-4Pharmaceutical Intermediate, Main Function: For the treatment of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH).
4BENZENEAZOMALONONITRILE6017-21-6Pharmaceutical Intermediate, Main Function: A key pharmaceutical intermediate for the synthesis of riociguat, and also used as an impurity reference standard for pharmaceutical quality control and testing.
51H-Pyrazolo[3,4-b]pyridine-3-carboximidamide, 1-[(2-fluorophenyl)methyl]-, hydrochloride (1:1)256499-19-1Pharmaceutical Intermediate, Main Function: For the treatment of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH).
61-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile256376-65-5Pharmaceutical Intermediate, Main Function: For the treatment of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH).
Vericiguat intermediate
No. Product Name CAS No. Application
75-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile1350653-26-7Pharmaceutical Intermediate, Main Function: For the treatment of adult patients with chronic heart failure with reduced ejection fraction.
85-fluoro-1-[(2-fluorophenyl)methyl]-1H-Pyrazolo[3,4-b]pyridine-3-carboximidamide-hydrochloride1426309-48-9Pharmaceutical Intermediate, Main Function: For the treatment of adult patients with chronic heart failure with reduced ejection fraction.
92-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine1350653-30-3Pharmaceutical Intermediate, Main Function: For the treatment of adult patients with chronic heart failure with reduced ejection fraction.
Tofacitinib intermediate
No. Product Name CAS No. Application
102,4-DICHLORO-7H-PYRROLO2,3-DPYRIMIDINE90213-66-4Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of various targeted kinase inhibitor drugs, playing a central role in the research and development of anti-tumor and immunomodulatory drugs.
114-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine123148-78-7Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of kinase inhibitor anti-tumor drugs and antiviral drugs.
Baricitinib intermediate
No. Product Name CAS No. Application
12(4-(1-(3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate1187595-90-9Pharmaceutical Intermediate, Main Function: For the treatment of various immune-mediated inflammatory diseases, with core indications including rheumatoid arthritis, moderate to severe atopic dermatitis, severe alopecia areata, and hospitalized adult COVID-19 patients requiring oxygen therapy.
13[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate1146629-77-7Pharmaceutical Intermediate, Main Function: For the treatment of JAK pathway-related diseases such as myelofibrosis and rheumatoid arthritis.
14(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)methyl pivalate1146629-75-5Pharmaceutical Intermediate, Main Function: Widely used in the research and development of innovative drugs for the treatment of immune and hematological diseases such as rheumatoid arthritis and myelofibrosis.
151-(1-ethoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole1029716-44-6Pharmaceutical Intermediate, Main Function: Widely used in the research and development of anti-tumor, anti-inflammatory and antiviral drugs.
162-(1-(ethylsulfonyl)azetidin-3-ylidene)acetonitrile1187595-85-2Pharmaceutical Intermediate, Main Function: For the synthesis of targeted drugs for the treatment of moderate to severe rheumatoid arthritis.
Ibrutinib intermediate
No. Product Name CAS No. Application
172-[Methoxy(4-phenoxyphenyl)Methylene]-Propanedinitrile330792-69-3Pharmaceutical Intermediate, Main Function: For the treatment of immune-mediated diseases such as rheumatoid arthritis and atopic dermatitis.
185-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile330792-70-6Pharmaceutical Intermediate, Main Function: For the treatment of immune-mediated diseases such as rheumatoid arthritis, moderate to severe atopic dermatitis, and severe alopecia areata.
19(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)pyrazolo [3,4-D]pyrimidin-4-ylamine1022150-12-4Pharmaceutical Intermediate, Main Function: For the synthesis of BTK inhibitor targeted anti-cancer drugs.
204-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine330786-24-8Pharmaceutical Intermediate, Main Function: For the treatment of hematological malignancies such as B-cell lymphoma and chronic lymphocytic leukemia.
Other intermediate
No. Product Name CAS No. Application
211-Indanone83-33-0Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of pharmaceuticals, fragrances and functional materials.
224-Hydroxy-D-(-)-2-phenylglycine22818-40-2Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of β-lactam antibiotics, particularly semi-synthetic penicillins and cephalosporins.
23(2R,3R,4R,5S,6S)-2-(AcetoxyMethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate461432-25-7Pharmaceutical Intermediate, Main Function: For the treatment of type 2 diabetes mellitus.
24(R)-2,3-Dihydro-1H-inden-1-amine hydrochloride10305-73-4Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of central nervous system (CNS) targeted drugs, particularly anti-Parkinson's disease drugs and monoamine oxidase-B (MAO-B) inhibitors.
25METHYL 3-OXOCYCLOBUTANECARBOXYLATE695-95-4Pharmaceutical Intermediate, Main Function: Widely used in the construction of drug molecules with cyclobutane skeletons, particularly valuable in the synthesis of antiviral drugs and small molecule targeted anti-cancer drugs.
262,3-Dihydro-1H-inden-1-amine hydrochloride32457-23-1Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of central nervous system (CNS) targeted drugs, particularly antidepressants and 5-HT receptor modulators.
271-AMINOINDANE HYDROCHLORIDE70146-15-5Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of central nervous system (CNS) targeted drugs.
28INDAZOL-1-YL-ACETIC ACID115822-57-6Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of bioactive heterocyclic compounds, particularly important in the research and development of anti-tumor, anti-inflammatory and neuroprotective drugs.
296-Bromo-2-pyridinecarbonitrile122918-25-6Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of bioactive molecules containing pyridine rings, particularly central in the research and development of anti-tumor drugs, kinase inhibitors and novel pesticides.
304-CHLOROTHIENO[2,3-D]PYRIMIDINE14080-59-2Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of kinase inhibitor targeted drugs, playing a core role in the research and development of anti-tumor, anti-inflammatory and antiviral innovative drugs.
31Cyclobutanecarboxylic acid, 3,3-difluoro-, methyl ester1234616-13-7Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of small molecule innovative drugs with high metabolic stability and enhanced target affinity, particularly important in the research and development of anti-tumor, antiviral and anti-inflammatory drugs.
323-Hydroxyazetidine hydrochloride18621-18-6Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of antiviral, anti-tumor and central nervous system (CNS) targeted drugs.
337-BROMO-IMIDAZO[1,2-A]PYRIDINE808744-34-5Pharmaceutical Intermediate, Main Function: Widely used in the construction of bioactive molecules containing nitrogen heterocycles, particularly valuable in the research and development of anti-tumor, antiviral and central nervous system (CNS) targeted drugs.
345-Aminolevulinic acid hydrochloride5451-09-2Pharmaceutical Intermediate, Main Function: Widely used in the fields of photodynamic therapy (PDT), agricultural biostimulants and medical diagnosis.
35N-(PyriMidin-5-ylMethyl)pyridin-2-aMine1383916-51-5Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of kinase inhibitor targeted drugs, playing a key role in the research and development of anti-tumor, anti-inflammatory and immunomodulatory innovative drugs.
362,3-dihydro-2,6-diMethyl-1H-Inden-1-one66309-83-9Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of pharmaceuticals, fragrances and functional materials.
37(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine752984-24-0Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of central nervous system (CNS) targeted drugs, particularly in the stereoselective synthesis of anti-Parkinson's disease drugs and antidepressants.
382,6-dimethyl-2,3-dihydro-1H-inden-1-amine1225478-65-8Pharmaceutical Intermediate, Main Function: Widely used in the synthesis of central nervous system (CNS) targeted drugs, playing a key role in the stereoselective synthesis of anti-Parkinson's disease drugs and antidepressants.
39(S)-(+)-2-hydroxy-3-methylbutyric acd17407-55-5Pharmaceutical Intermediate, Main Function: Widely used as pharmaceutical and pesticide intermediates.
40L(+)-allo-Threonine28954-12-3Pharmaceutical Intermediate, Main Function: As pharmaceutical and biological research intermediates, playing important roles in antibiotic synthesis, metabolic research and chiral drug development.
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